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Significant association between GSTA4 mRNA expression and DNA methylation. (A) mRNA expression levels in the IA group were higher than that in controls. (B) mRNA expression levels in women IAs were higher than that in women controls. (C) No statistical significance was observed between men IAs and men controls. (D) GSTA4 mRNA expression was correlated with its DNA methylation levels in all participants. (E) DNA hypomethylation induced by AZA increased the mRNA expression of the GSTA4 gene in <t>HBVSMCs.</t> (F,G) GSTA4 methylation levels in between smoker and non-smoker group. (H) GSTA4 mRNA expression between smoker and non-smoker groups.
Human Brain Vascular Smooth Muscle Cells (Hbvsmcs) Catalog #1100, supplied by ScienCell, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
human brain vascular smooth muscle cells (hbvsmcs) catalog #1100 - by Bioz Stars, 2026-04
90/100 stars
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Significant association between GSTA4 mRNA expression and DNA methylation. (A) mRNA expression levels in the IA group were higher than that in controls. (B) mRNA expression levels in women IAs were higher than that in women controls. (C) No statistical significance was observed between men IAs and men controls. (D) GSTA4 mRNA expression was correlated with its DNA methylation levels in all participants. (E) DNA hypomethylation induced by AZA increased the mRNA expression of the GSTA4 gene in HBVSMCs. (F,G) GSTA4 methylation levels in between smoker and non-smoker group. (H) GSTA4 mRNA expression between smoker and non-smoker groups.

Journal: Frontiers in Genetics

Article Title: DNA methylation and mRNA expression of glutathione S-transferase alpha 4 are associated with intracranial aneurysms in a gender-dependent manner

doi: 10.3389/fgene.2022.1079455

Figure Lengend Snippet: Significant association between GSTA4 mRNA expression and DNA methylation. (A) mRNA expression levels in the IA group were higher than that in controls. (B) mRNA expression levels in women IAs were higher than that in women controls. (C) No statistical significance was observed between men IAs and men controls. (D) GSTA4 mRNA expression was correlated with its DNA methylation levels in all participants. (E) DNA hypomethylation induced by AZA increased the mRNA expression of the GSTA4 gene in HBVSMCs. (F,G) GSTA4 methylation levels in between smoker and non-smoker group. (H) GSTA4 mRNA expression between smoker and non-smoker groups.

Article Snippet: Human brain vascular smooth muscle cells (HBVSMCs) (Catalog #1100, ScienCell, Carlsbad, Canada) were used in this study.

Techniques: Expressing, DNA Methylation Assay, Methylation